Example sentences for: adenovirus-mediated

How can you use “adenovirus-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although the mechanism of the contralateral effect is unclear, we have demonstrated that adoptive transfer of dendritic cells from animals treated with adenovirus-mediated gene transfer of v-IL-10 to untreated immunized animals is able to confer a therapeutic effect (unpublished data).

  • We have demonstrated previously that periarticular injection of adenovirus-mediated gene transfer of v-IL-10 into the hind paws of mice with early-stage arthritis was able to confer a therapeutic effect in the untreated front paws.

  • To examine the effects of TGF-β1 on joint pathology, we used adenovirus-mediated intra-articular gene delivery to confer sustained intra-articular TGF-β1 expression in both naïve and arthritic rabbit knee joints.

  • The use of adenovirus-mediated gene therapy in treating brain tumors has been reported to lead to active brain inflammation as well as persistent (up to 3 months after treatment) transgene expression [ 25].

  • In animal models of arthritis, systemic treatment with IL-10 and adenovirus-mediated transfer of viral IL-10 moderately suppresses the development of arthritis, but is significantly more effective when combined with IL-4 [ 19 20 21 22 23 24 ] . The evidence for the importance of IL-10 is further supported by the fact that in vivo anti-IL-10 treatment accelerates disease in collagen-induced arthritis (CIA) [ 22 ] .


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