Example sentences for: adenomas

How can you use “adenomas” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Polyps (multiple) are generally localized to the small intestine in Min /+ mice, opposed to the colons of FAP suffers [ 27 ] . In Min /+ mice adenoma formation is thought to occur within the first few weeks of life, with a full compliment of adenomas being attained by approximately 9 weeks of age (60-67 days of age) [ 6 28 ] . Following this time, adenoma multiplicity is thought not to change, however, adenoma size may still increase [ 6 28 ] . Min /+ mice are also normally found to develop anaemia by 60 days of age and possess a shortened life span of roughly 120 days (17 weeks) [ 29 ] .

  • p27 Kip1knockout mice display internal organ hyperplasia and are highly prone to pituitary adenomas [ 5 6 7 ] . In human cancers, such as breast [ 8 ] , prostate [ 9 ] , colorectal [ 10 ] , and others, low levels of p27 Kip1expression correlate with decreased survival rates.

  • In the intervention trial, treatment occurred at a time when small, encapsulated adenomas are forming (week 10 for Rip1-Tag2 mice).

  • A wild type genotype was assumed, since no existing data suggests or indicates that aspirin is able to cause complete elimination of adenomas in this model.

  • The NSAID sulindac has been shown to cause regression of colorectal adenomas of patients with hereditary forms of polyposis (Familial Adenomatous Polyposis (FAP) and Gardner's Syndrome) [ 17 18 19 ] and in sporadic colorectal adenomas [ 20 ] . In addition, case reports have demonstrated that indomethacin and sulindac were effective co-therapy agents in the treatment of desmoid tumours [ 21 22 ] . Finally, the inclusion either of indomethacin, naproxen or sulindac in the chemotherapy regiment of gastric carcinoma patients resulted in a significant increase in survival; 30 months versus 6 months when NSAIDs included in treatment regime [ 22 ] .


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