Words similar to adducts

Example sentences for: adducts

How can you use “adducts” in a sentence? Here are some example sentences to help you improve your vocabulary:

It would be of great interest to study the Ogg1 mutant mice to determine whether an increase level of 8-OH-dG adducts predisposes to diabetes.
However, the nuclear localization of 8-OH-dG [ 32 ] and the increased Ogg1 reported here are consistent with a model in which mitochondrial Ogg1 is up-regulated but nuclear Ogg1 is not, leading to an increase in nuclear but not mitochondrial 8-OH-dG adducts [ 32 ] . Further studies will be required to resolve this issue, but β-cells in type 2 diabetes may well suffer from both nuclear and mitochondrial DNA damage, leading to decreased β-cell function and eventual loss of β-cell mass.
Subsequent experiments with immunofluorescent staining indicated that 1.5 mM H 2 O 2 treatment of ARPE-19 cells for 4 hours led to the formation of 4-HNE protein adducts both in the cytoplasm and nucleus, presumably as a result of lipid-peroxidation (Fig.
The standard treatment for advanced-stage cervix cancer has been the combination of radical surgery and radiotherapy [ 36 ] . The utility of cytotoxic chemotherapy in patients with advanced CC has been recognized recently [ 37 ] . Thus, the epigenetic gene silencing of MGMT , although in a small proportion, may serve as indicator of responsiveness to treatment with chemotherapeutic drugs that cause DNA adducts in CC.
Such an apoptotic defect could account for the increasing intensity of Ogg1 staining, following accumulated levels of 8-OH-dG adducts with longer duration of diabetes.