Words similar to acute-phase

Example sentences for: acute-phase

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SPI-3 has been shown to be a downstream target of both the inflammatory acute-phase regulators TNFα and IL-6 [ 33 ] . Positive correlation with an intermediate conductance calcium-activated potassium channel SMIK (AF190458) was common to the metrics related to vacuole density, area % vacuoles and vacuoles/mm 2. CCl 4 treatment perturbs the balance of many serum electrolytes [ 34 ] , and an increase in the SMIK channel might help re-establish normal potassium homeostasis as the liver recovers from the toxic stress.
Tumor necrosis factor (TNF) has been implicated in the development and pathogenicity of infectious diseases and autoimmune disorders, such as septic shock, arthritis, and hypotension [ 1 2 3 4 ] . It plays a pivotal role in the inflammatory cascade and, together with IL-1 and IL-6, has been shown to mediate the acute-phase response [ 5 6 ] . Confirmation of its significance in disease comes from the success of clinical trials using anti-TNF therapy to treat rheumatoid arthritis and Crohn's disease [ 7 8 9 10 ] .
The inability of rhIL-11 to bring about a statistically significant improvement in the ACR 20% criteria may also be the result of an inability of rhIL-11 to stimulate the synthesis of acute-phase proteins, of the significant clinical response of several placebo-treated patients, or of a lack of adequate power of the study to show efficacy.