Example sentences for: active-site

How can you use “active-site” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It exhibits signature motifs corresponding to the regions of the active-site lysine and the interdomain interface [ 3].

  • This, together with the phyletic distributution of the AraC and 2OG-Fe(II) dioxygenase superfamilies, leads us to speculate that the 2OG-Fe(II) dioxygenase superfamily evolved from the AraC-like superfamily in bacteria through drastic sequence divergence that eliminated significant sequence similarity, followed by fixation of the modified active-site configuration.

  • Here, using sequence profile searches, we show that many other protein families contain the same constellation of active-site residues and are predicted to adopt the same fold.

  • The KilA-N, APSES and TEN-terminal domains lack the equivalent residues of the specific active-site extension of the LAGLIDADG nucleases, suggesting that the former domains do not possess nuclease activity.

  • Although human biochemists can depress activity more than 10 5-fold in Fhit [ 35, 36] and Hint [ 30] with a single active-site His mutation, hens apparently continued to peck at the sequence of Hint, altering all four of the absolutely conserved His residues.


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