Example sentences for: activator

How can you use “activator” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Except for the trials of intravenous recombinant tissue-plasminogen activator (rt-PA) in the treatment of ischemic stroke within the first 3 h [ 1], this traditional approach has lead to no approved therapies for stroke, and has lead to a great degree of pessimism with regard to thrombolysis beyond 3 h and with regard to the concept of neuroprotection in stroke.

  • al (1996) reported that the Myelodysplasia syndrome 1(MDS1) gene spliced into exon 2 of the adjacent Ecotropic viral integration site 1 (EVI1) gene, producing a unique transcript containing an ORF that produces a GATA-binding transcriptional activator [ 30 31 ] . The human Galactose-1-phosphate uridylytransferase (GALT) gene produces an intergenic transcript by skipping its last exon and splicing into exon 2 of Interleukin-11 receptor α-chain (IL-11Rα) [ 32 ] . This produces an intergenic transcript that keeps the endogenous frame of both genes, thereby coding for a theoretical protein with domains from both proteins.

  • These include: a Hh-protein-blocking antibody, 5E1 [ 23 ] ; a natural product derivative, cyclopamine [ 9 10 ] that has recently been shown to act downstream of Ptc, perhaps at the level of Smo [ 11 ] ; a recently identified synthetic small-molecule inhibitor, Cur61414, which has inhibitory properties similar to cyclopamine [ 17 ] ; and forskolin, an adenylate cyclase/protein kinase A activator that is thought to block Hh signaling by stimulating degradation of members of the Gli family of transcriptional activators [ 2 ] .

  • Our experiments in a reconstituted transcription system lacking contaminating AP-1 proteins and using DNA templates with high affinity NFAT sites demonstrate that NFATp can function as a transcriptional activator on its own.

  • signal transducer and activator of transcription 1 STAT1

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