Example sentences for: activation

How can you use “activation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For studies of the transcriptional activation properties of the fusion proteins, 1 μg of the C/EBP-TATA vector [ 45 ] was co-transfected and transcriptional activity was assessed by measuring the amount of chloramphenicol acetyltransferase reporter expressed with and without C/EBPα expression [ 45 ] .

  • It is important to discriminate these results from other analyses of T cell activation that have employed antigen receptor activation, as opposed to IL-2.

  • The results presented such far indicate that PMA decreases electrical excitation of β-cells and this effect is independent on PKC activation.

  • It was reported that PPAR activation could down-regulate the activity of AP-1 by interfering with the functions of c-jun [ 36 37 ] . Therefore, the following set of experiments was designed to test if PPAR activation could reduce c-jun activation in 25-OH-cholesterol treated microglia.

  • APC mutations have been identified in medulloblastoma cell lines and up to 4% of sporadic medulloblastomas [ 16 17 ] . Furthermore, point mutations or small deletions in β- catenin exon 3 have been identified in 5-10% of sporadic medulloblastomas and in supratentorial primitive neuroectodermal tumors (PNETs) [ 17 18 19 ] . Finally, large deletions in AXIN were recently found in 12% of sporadic medulloblastomas [ 20 ] . In the absence of Wnt signaling β-catenin is sequestered in the cytoplasm, and nuclear translocation of β-catenin has been used to monitor activation of the Wnt pathway in a number of different tumor types.


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