Example sentences for: activation

How can you use “activation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Protein kinase pathways play major roles in cPLA 2 activation, and regulation by the mitogen-activated protein kinase kinase (MEK) /extracellular-signal regulated kinase (ERK) signaling pathway has received particular attention.

  • Mutagenesis of the Fnr recognition sequence at the dmsA promoter region confirmed the contribution of Fnr in the 100-fold activation of dmsABC expression and explored the DNA sequence and spacing requirements for the Fnr recognition site at the P1 promoter.

  • HSP70 is one of the first genes to be expressed following zygotic gene activation in the two-cell mouse embryo [ 38 39 40 ] and appears to play a role in developmental processes in a number of species [ 50 51 52 53 ] . Endogenous HSP90 has also been implicated in developmental regulation in the mouse [ 52 ] , and GRP78 is described as having a stress-response function during avian development [ 54 ] . Activation of the zygotic genome initiates an accumulation of embryonic transcripts in the early two-cell embryo, and this likely requires machinery to ensure the accurate translation and folding of nascent proteins.

  • Significantly, among the five subtypes of muscarinic ACh receptors (MAChRs), Ml and M3 receptors have been shown to efficiently activate PLD (and PKC) in various cell types [ 26 27 28 29 30 ] , whereas activation of PLD by M2 and M4 receptors is less robust [ 26 ] . These observations suggest that in a cholinergic synapse, ACh released into the synaptic cleft might stimulate PLD activity leading to a release of choline that could be used for ACh synthesis.

  • Activation of NFκB involves the increased phosphorylation and proteolytic degradation of IκB.


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