Words similar to acmb
Example sentences for: acmb
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We show that this superfamily, in addition to the well characterized P60-related peptidoglycan peptidases, includes divergent cell-wall hydrolases typified by AcmB/LytN, eukaryotic proteins such as LRAT, Egl-26 and their relatives, amidase domains of GSPSs, and several other uncharacterized bacterial proteins.
Two major subfamilies within this family, typified respectively by AcmB and S. aureus LytN, are predominantly restricted to the Gram-positive bacteria, and function as cell-wall hydrolases.
The AcmB subfamily shows a lineage-specific expansion in the genome of S. aureus , with around seven paralogs.
The first recognizable secondary structure element in this domain is an α-helix that is present in practically all members of this superfamily, with the exception of a few members of the AcmB family from Staphylococcus aureus (Figures 1, 2), where it appears to have entirely degenerated.
The phyletic distribution suggests that the AcmB/LytN-like family emerged early in the Gram-positive lineage, through rapid sequence divergence.