Words similar to achbp

Example sentences for: achbp

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These amino acids form a cluster in the proposed acetylcholine binding domain of AChBP similar to that proposed in our model.
In addition, our data support the existence of a loop structure in this region as has been hypothesized for the nAChR and identified in a homologous AChBP [ 12 23 24 ] .
The interaction is included in the model based on structural information obtained from the crystal structure of AChBP [ 27 ] . The region of this protein homologous to loop E and loop D of the 5-HT 3A receptor suggests a loop structure from Y140 to Y152 and a 3-residue turn containing a glycine at position 147 and the β-strand from W89 through Y93 oriented as shown in Figure 6. The orientation of lerisetron between W89 and Y142A as shown would enable the N-benzyl group to be positioned in close proximity to R91.
R91, E106, F107, W183 and several residues adjacent to the M1 region have all been demonstrated to alter the action of 5-HT and/or m CPBG [ 20 21 25 26 ] . Within the crystal structure of the AChBP, homologous residues are located in the apparent binding site [ 24 ] . The effects of agonist on the 5-HT 3 R are mediated by their interaction with these binding site residues, resulting in stable receptor conformations, including the channel open state.
[ 6 ] that differed from the AChBP template residue were energy-minimized in the internal coordinates space using ICM global conformational search algorithm.