Example sentences for: acetylcholine

How can you use “acetylcholine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Similarly, acetylcholine and nicotine were docked into the agonist binding site at the alpha3-beta2, alpha4-beta4 and alpha7-alpha7 interfaces.

  • Oocytes contain endogenous insulin and IGF-1 receptors [ 14 ] . They also have many of the proteins in the RAS and MAP kinase pathways, which have been implicated in cell cycle control and re-entry into meiosis [ 15 16 ] .. We expressed two GPCRs, a serotonin receptor (5-HT 2C ) and an M1 muscarinic acetylcholine (Ach) receptor.

  • Again, the predicted energies of acetylcholine and nicotine binding to AChBP are close to those for binding to nAChRs (Table 1- top).

  • Based on data obtained from affinity labeling and site directed mutagenesis studies, several regions of the nicotinic acetylcholine receptor have been implicated in ligand binding [ 10 ] . Six essential loops appear to contribute to the binding site with the position of each loop differing slightly depending on whether the receptor is heteromeric or homomeric [ 4 ] . For homomeric receptors such as the α7 nAChR, the loops are identified as A, B, C, D, E and F [ 4 11 ] . The amino acids that interact with ligands presumably extend into the binding site from these loops.

  • When activated, either by acetylcholine or by nicotine, they allow selected ions to flow across the cell membrane.

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