Example sentences for: aberrant

How can you use “aberrant” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We also speculate that Golgi fragmentation in cell death might participate in sustaining autoantibody response to the Golgi complex in aberrant disease states characterized by unregulated cell death resulting from injury or infection or defective clearance of dying cells.

  • The hallmark of opioid addiction is psychological dependence manifested by a behavioral syndrome of continued, compulsive drug use, despite harm [ 28 ] . Care must be taken to differentiate a true addiction (substance use disorder) from pseudo addiction due to under treatment of pain or other aberrant drug-related behaviors [ 29 ] .

  • A nonrandom pattern of promoter hypermethylation has been noted in specific genes in specific tumor types, although some genes are commonly methylated in diverse tumors [ 3 4 ] . The extent of aberrant promoter hypermethylation and its association with loss of gene function in cancer suggests that CpG island methylation is an important mechanism in inactivating tumor suppressor genes (TSGs).

  • The immunolocalization of RhoA in normal and C3 treated cells did not appear drastically different in that RhoA was apparent in both normal and aberrant pseudopodial extensions.

  • A 2-fold to 3-fold increase of β-catenin level in the mammary glands of transgenic mice also results in aberrant differentiation and tumors [ 34 35 ] . Thus while it is possible that a greater than 2-fold increase in β-catenin level would have a neoplastic effect on adult neurons, evidence from other transgenic models suggests the increased protein level in our mice could be sufficient for tumor promotion.

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