Example sentences for: abcg

How can you use “abcg” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, a literature search revealed that a few strains of rats, studied primarily for investigation of hypertension and stroke, have been reported to be sitosterolemic as well [ 15 16 ] . We hypothesised that these rat strains may be mutated in either Abcg5 or Abcg8 . Tissue (and plasma) plant sterol levels in the Wistar Kyoto (WKY) rat, the spontaneously hypertensive rat (SHR) and the stroke-prone spontaneously hypertensive rat (SHRSP) were significantly higher than in Wistar and WKA rats fed either a regular chow diet or diets that have higher plant sterols and these were correlated with increased death, or red cell hemolysis etc. [ 15 16 17 18 19 20 21 22 ] . Dietary sterol absorption rates were increased, with a decrease in sterol excretion [ 16 ] , characteristics similar to that observed in sitosterolemic patients.

  • Both of these methods gave consistent results and indicated that expression of Abcg5 was increased approximately 2-fold in the SHR but not the Wistar or SD (Fig.

  • Additionally, both the mouse and human Abcg8 genes have alternatively spliced mRNA, involving a CAG repeat at exon 2 and exon 8 splice acceptor sites respectively [ 12 14 ] . However, despite the presence of such a repeat at the rat exon 2 splice acceptor site for Abcg8 (Table 2), none of the rat mRNAs showed any heterogeneity of splice-site selection at this site.

  • Rat Abcg5 and Abcg8 mRNA expression patterns were determined, using a commercial multiple tissue poly A +Northern filter.

  • The GH rat was selected for systolic hypertension that increased with successive generations and maintained through filial matings [ 45 ] . In view of this, the Gly583Cys missense mutation of Abcg5 might result from occurrence of a de novo mutation during breeding at the stage of developing inbred WKY strains and propagated into the SHR and SHRSP lines.


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